Assessing the frequency of Gastroesophageal Reflux Disease among Chronic Obstructive Pulmonary Disease Patients
Keywords:
COPD, Gastroesophageal Reflux, Asthma , Forced Expiratory VolumeAbstract
Background: A minimum of 170 million individuals worldwide are thought to have chronic obstructive pulmonary disease (COPD), a common lung illness marked by reversible airflow limitation and chronic inflammation of the airways. Recent research indicated that symptoms associated with gastroesophageal reflux disease (GERD) are more prevalent in individuals with COPD. Objective: Objective of the present study was to find out the frequency of GERD in COPD patients. Methodology: The study was conducted at a Rehman medical institute in Pakistan from January 2022 to June 2022, using a cross-sectional design. Data was collected from 160 COPD patients, who underwent a comprehensive clinical examination and history. All these patients were assessed for GERD through a frequency scale for the symptoms of GERD (F.S.S.G questionnaire) instead of endoscopy and PH assessment. Spirometry was performed on each patient, and the findings were analyzed by a fellow specialist. The study also determined the frequency of GERD in COPD patients. SPSS version 23 was used for data analysis. Results: The current cross-sectional study includes a total of 160 participants including both males and females selected through a purposive sampling technique. Among them, 63.75% were males and 36.24% were female participants. The overall prevalence of GERD among the participants was 45%. GERD was found in 31.94%, 40.27% and 16. 66% among moderate, severe, and very severe cases of COPD. Conclusion: The study findings indicate that GERD was found in 45% of individuals with COPD. This underscores the importance for healthcare providers to thoroughly assess COPD patients for GERD to prevent further complications and enhance their quality of life.References
GBD 2015 Chronic Respiratory Disease Collaborators. Global, regional, and national deaths, prevalence, disability-adjusted life years, and years lived with disability for chronic obstructive pulmonary disease and asthma, 1990–2015: a systematic analysis for the Global Burden of Disease Study 2015. Lancet Respir Med. 2017;5(9):691.
Vogelmeier CF, Criner GJ, Martinez FJ, Anzueto A, Barnes PJ, Bourbeau J, et al. Global strategy for the diagnosis, management, and prevention of chronic obstructive lung disease 2017 report. GOLD executive summary. Am J Respir Crit Care Med. 2017;195(5):557-82.
Fang X, Wang X, Bai C. COPD in China: the burden and importance of proper management. Chest. 2011;139(4):920-9.
Khan HN, Suleman A, Ullah R, Abdullah A, Naz S. Estores DS. Symptom predictability in gastroesophageal reflux disease and role of proton pump inhibitor test. Gastroenterol Clin N Am. 2014;43:27–38. 7.
Khan HN, Suleman A, Ullah R, Abdullah A, Naz S. Gastro esophageal reflux diseases in chronic obstructive pulmonary disease patients. J Ayub Med Coll Abbottabad. 2017;30(1):64-6.
Sanchez J, Schumann DM, Karakioulaki M, Papakonstantinou E, Rassouli F, Frasnelli M,. Laryngopharyngeal reflux in chronic obstructive pulmonary disease-a multi-centre study. Respir Res. 2020;21:1-6.
Biener AI, Decker SL, Rohde F. Prevalence and treatment of chronic obstructive pulmonary disease (COPD) in the United States. JAMA. 2019 ;322(7):602-22.
Safiri S, Carson-Chahhoud K, Noori M, Nejadghaderi SA, Sullman MJ, Heris JA, et al. Burden of chronic obstructive pulmonary disease and its attributable risk factors in 204 countries and territories, 1990-2019: results from the Global Burden of Disease Study 2019. BMJ. 2022;27;378.
Pumar MI, Gray CR, Walsh JR, Yang IA, Rolls TA, Ward DL. Anxiety and depression—Important psychological comorbidities of COPD. J Thorac Dis. 2014;6(11):1615.
Wang J, Willis K, Barson E, Smallwood N. The complexity of mental health care for people with COPD: a qualitative study of clinicians’ perspectives. NPJ Prim. Care Respir Med.2021;31(1):40.
Weiss JR, Serdenes R, Madtha U, Zhao H, Kim V, Lopez-Pastrana J, Eakin MN, et al. Association Among Chronic Obstructive Pulmonary Disease Severity, Exacerbation Risk, and Anxiety and Depression Symptoms in the SPIROMICS Cohort. J Acad Consult Liaison Psychiatry. 2023;64(1):45-57.
Yu F, Huang Q, Ye Y, Zhang L. Effectiveness of proton-pump inhibitors in chronic obstructive pulmonary disease: a meta-analysis of randomized controlled trials. Front Med. 2022;9:841155.
Quaderi SA, Hurst JR. The unmet global burden of COPD. Glob Health Epidemiol Genom.. 2018;3:e4.
Hsu CK, Lai CC, Wang K, Chen L. Risk of lung cancer in patients with gastro-esophageal reflux disease: a population-based cohort study. Peer J. 2016;4:e2753.
Ghebre YT, Raghu G. Idiopathic pulmonary fibrosis: novel concepts of proton pump inhibitors as antifibrotic drugs. Am J Respir Crit Care Med. 2016;193(12):1345-52.
Lin HC, Xirasagar S, Chung SD, Huang CC, Tsai MC, Chen CH. Fewer acute respiratory infection episodes among patients receiving treatment for gastroesophageal reflux disease. PloS One. 2017;12(2):e0172436.
Hafeez S, Butt A, Hussain A, Hashim MA, Ahmad S, Ahmad A. Gastroesophageal Reflux Disease in Patients With Chronic Obstructive Pulmonary Disease. APIMS. 2021;17(1):71-4.
Kakar IA, Baqi A, Azim N, Ahmad W, Shaukat Z, Shahab K. Frequency of Gastroesophageal Reflux Disease in Chronic Obstructive Pulmonary Disease Patients. Pak J Med Heal Sci. 2022;16(12):397-12.
Huang C, Liu Y, Shi G. A systematic review with meta-analysis of gastroesophageal reflux disease and exacerbations of chronic obstructive pulmonary disease. BMC Pulm. Med. 2020 ;20:1-9.
Broers C, Tack J, Pauwels A. Gastro-oesophageal reflux disease in asthma and chronic obstructive pulmonary disease. Aliment Pharmacol Ther. 2018;47(2):176-91.
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2023 Pakistan Journal of Chest Medicine

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.


