Association of Baseline Hematological Parameters with Thromboembolic Events in Hospitalized COVID-19 Patients
Keywords:
COVID-19, Thromboembolic Events, D-Dimer, MPVAbstract
Background: COVID-19 carries an increased risk of blood clot complications because of its effects on the body's inflammation and clotting processes. Identifying patients who are at risk as early as possible is crucial for healthcare providers. Regular blood tests can provide useful information to predict these risks. Objective: To determine the frequency of in-hospital thromboembolic events among COVID-19 patients and assess the influence of blood parameters, measured at the time of admission, on the occurrence of these events. Methodology: This retrospective study included 364 hospitalized COVID-19 patients. Demographic, clinical, and laboratory data at admission were collected from medical records. Thromboembolic events were documented and confirmed through clinical and imaging findings. Logistic regression analysis was used to identify independent predictors. Results: Thromboembolic events occurred in 6.6% of hospitalized COVID-19 patients, with myocardial infarction being the most common. Patients with such events had significantly lower hemoglobin, higher MPV, and elevated D-dimer levels. Age, low hemoglobin, and high MPV were identified as independent predictors. No significant differences were observed in C-reactive protein, LDH, or total WBC count. Conclusion: Age, low hemoglobin, and high MPV are independent predictors of thromboembolic events in hospitalized COVID-19 patients. These common blood parameters may help identify risk early. Including them in clinical assessments can improve prevention measures. More prospective studies are necessary to confirm these findings.References
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