Spectrum of Radiologic Findings in Atypical Pulmonary Metastases
DOI:
https://doi.org/10.1996/pjcm.v28i3.824Keywords:
Pulmonary Metastasis, Patterns, Atypical Radiologic FeaturesAbstract
Background: Atypical pulmonary metastases present a diverse range of radiologic findings in the lungs, deviating from the typical patterns of metastatic disease. These unique radiological characteristics play a pivotal role in their diagnosis and differentiation from other lung pathologies. Objective: The goal is to show the various imaging patterns for pulmonary metastases from various primary malignancies. Methodology: This study is a retrospective descriptive analysis in which we examined 30 cases of pulmonary metastasis originating from various primary malignancies. The study was conducted at the Radiology departments of Khyber Teaching Hospital, Peshawar and Hayatabad Medical Complex, Mardan, between July 2017 and August 2021. Our focus was on identifying and documenting the unique radiologic characteristics associated with metastases originating from different primary cancers. Results: In our institution, we conducted an analysis of 30 cases of pulmonary metastases. Among these cases, we observed varying patterns of metastatic spread. Specifically, 4 (14%) cases were associated with Renal cell carcinoma, 2 (7%) cases with testicular germ cell tumours, 4 (13%) cases with thyroid cancer, 2 (7%) cases with osteosarcoma, 4 (13%) cases with GI tract adenocarcinoma, 3 (10%) cases with gynaecological malignancies, 1 (3%) case with femoral vein leiomyosarcoma, 4 (13%) cases with breast cancer, 1 (3%) case with lymphoma, and 5 (17%) cases with lung carcinoma. These cases exhibited a range of pulmonary metastatic patterns alongside the typical presentation characterized by multiple soft tissue density nodules. Conclusion: The usual radiologic signs of lung metastasis are several spherical, variable-sized nodules and widespread interstitial thickening. It is challenging to diagnose lung metastases because of various patterns. Therefore, understanding the various pulmonary metastasis patterns from various primary aids helps in the early detection of metastases. Keywords: Pulmonary Metastasis; Patterns; Atypical Radiologic Features.References
Gulzar A, Xu J, Wang C, He F, Yang D, Gai S, et al. Tumour microenvironment responsive nanoconstructs for cancer theranostic. Nano today. 2019;26:16-56.
Herold CJ, Lewin JS, Wibmer AG, Thrall JH, Krestin GP, Dixon AK, et al. Imaging in the age of precision medicine: summary of the proceedings of the 10th Biannual Symposium of the International Society for Strategic Studies in Radiology. Radiol. 2016;279(1):226-38.
Frazier AA, Hossain R. A Spectrum of Metastatic Disease in the Chest: Insights for the Radiologist. In Seminars in Roentgenology. 2020; 55(1): 51-59). WB Saunders.
Sewchuran T. Solid to cystic: A case report of imaging findings of atypical lung metastases. J Radiol. 2019;23(1).
Gagnon MH, Wallace AB, Yedururi S, Khanna G. Atypical pulmonary metastases in children: pictorial review of imaging patterns. Pediat Radiol. 2021;51:131-9.
Irby DM. Excellence in clinical teaching: knowledge transformation and development required. Med Edu. 2014;48(8):776-84.
Thali MJ, Viner MD, Brogdon BG, editors. Brogdon's forensic radiology. CRC press; 2010.
Patel VL, Kaufman DR, Arocha JF. Emerging paradigms of cognition in medical decision-making. J Biomed Inf. 2002;35(1):52-75.
Ponikowski P, Anker SD, Al-Habib KF, Cowie MR, Force TL, Hu S, et al. Heart failure: preventing disease and death worldwide. ESC Heart Fail. 2014;1(1):4-25.
Lateef F. Patient expectations and the paradigm shift of care in emergency medicine. J Emerg Trauma Shock. 2011;4(2):163.
Tappenden KA, Quatrara B, Parkhurst ML, Malone AM, Fanjiang G, Ziegler TR. Critical role of nutrition in improving quality of care: an interdisciplinary call to action to address adult hospital malnutrition. J Acad Nutr Diet. 2013;113(9):1219-37.
Chikarmane SA, Tirumani SH, Howard SA, Jagannathan JP, DiPiro PJ. Metastatic patterns of breast cancer subtypes: what radiologists should know in the era of personalized cancer medicine. Clinic Radiol. 2015;70(1):1-0.
Brufau BP, Cerqueda CS, Villalba LB, Izquierdo RS, González BM, Molina CN. Metastatic renal cell carcinoma: radiologic findings and assessment of response to targeted antiangiogenic therapy by using multidetector CT. Radiographics. 2013;33(6):1691-716.
MartÃnez-Jiménez S, Rosado-de-Christenson ML, Walker CM, Kunin JR, Betancourt SL, Shoup BL, Pettavel PP. Imaging features of thoracic metastases from gynecologic neoplasms. Radiographics. 2014;34(6):1742-54.
Seo JB, Im JG, Goo JM, Chung MJ, Kim MY. Atypical pulmonary metastases: spectrum of radiologic findings. Radiographics. 2001;21(2):403-17.
Wood MJ, Thomas R, Howard SA, Braschi-Amirfarzan M. Imaging of metastatic germ cell tumors in male patients from initial diagnosis to treatment-related toxicities: a primer for radiologists. Am J Roentgenol. 2020;214(1):24-33.
Angirish B, Sanghavi P, Jankharia B. Pulmonary manifestations of lymphoma: A pictorial essay. Lung India. 2020;37(3):263.
Purandare NC, Rangarajan V. Imaging of lung cancer: Implications on staging and management. Indian J Radiol Imaging. 2015;25(02):109-20.
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2022 Pakistan Journal of Chest Medicine
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
